Reversing ageing (Is p63 the answer?): p63 inhibits the decline in mitochondrial function with age via induction of its target gene, 23/December/2013, 10.48 am

Prof. DA Sinclair (from Harvard Medical School, Boston, USA) has published a paper in the Journal Cell stating that “Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging.”  This study suggests that declining NAD+ levels accelarates ageing, while increasing NAD+ levels reverses ageing. In connection with this finding, Dr L Boominathan, Director-cum-chief scientist of GBMD, reports that: Reversing ageing (Is p63 the answer?): p63 inhibits the decline in mitochondrial function with age via induction of its target gene.  This finding suggests that p63 increases NAD+ levels via up regulation of its target gene. This exciting finding opens up a new therapeutic opportunity to reverse ageing by modulating p63 levels. 

Idea Proposed by: Dr L Boominathan Ph.D.

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To cite: Boominathan, Reversing ageing (Is p63 the answer?): p63 inhibits the decline in mitochondrial function with age via induction of its target gene, 23/December/2013, 10.48 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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