Nobel laureate Sharp PA has reported that "Let-7 represses Nr6a1 and a mid-gestation developmental program in adult cells"

Interrupting the mid-gestation developmental program: p53/p63/p73 promotes continual suppression of embroyonic gene expression in adult cells by regulating the Let-7-Nr6a1 pathway,
July 10, 2013
p53 inhibits proliferation, activates G1-S Restriction Point, and promotes ESC Differentiation by suppressing the expression of miR-302, 10/July/2013, 21.46
July 10, 2013
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Dr L Boomianthan PhD, Chief-Scientist-cum-Director of GBMD, reports that p53/p63/p73 promotes continual suppression of embroyonic gene expression in adult cells by regulating the Let-7-Nr6a1 pathway through its target genes. 

http://genomediscovery.org/interrupting-the-mid-gestation-developmental-program-p53p63p73-promotes-continual-suppression-of-embroyonic-gene-expression-in-adult-cells-by-regulating-the-let-7-nr6a1-pathway/

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