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Noble Laureate Prof. Carol W Greider  had reported in the journal Molecular Cell  (2006 Nov 3;24(3):423-32) that the cyclin-dependent kinase CDK1 regulates teomere elongation. Subsequently, Noble Laureate Prof. Elizabeth H. Blackburn had reported in the journal Cell (2009 Jan 9;136(1):50-61) that  Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progressionBased on these observations, here, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports that the tumor suppressor p53 controls telomere elongation by suppressing CDK1 expression through its target miRNA.
 

Idea Proposed byDr L Boominathan Ph.D.

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To citeBoominathan, The tumor suppressor p53 controls telomere elongation by suppressing CDK1 expession through its target miRNA, 17/August/2013, 17.04, http://genomediscovery.org

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