Thomson Reuter’s Nobel prize Nominee (2013) Prof. Adrian P. Bird (Univ of Edinburg, UK) has published a paper in Molecular Cell stating that “Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the methylation pattern” (Bird AP. Mol Cell. 2010 Feb 26;37(4):457-68).
In relation to this finding, Dr Boominathan, Director-cum-chief scientist of GBMD, reports that the tumor suppressor p53 homologue, p63 regulates MeCP2 expression through its target gene miR-181. This finding suggests that expression of p63 may have greater impact on the methylation pattern.
Idea Proposed by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
To cite: Boominathan, The Follow-up work of Pro-Nob(Bird)el’s favorite: The tumor suppressor p63 regulates MeCP2 expression through its target gene miR-181, 7/October/2013, 12.50 pm., Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
* Research cooperation