Noble Laureate in Medicine (1998) Prof. Dr Ferid M (The University of Texas, Houston, Texas, USA) has suggested in a number of papers that inhibition of NOS2 (Nitric oxide synthase) may have a therapeutic value in a number of cancers.
In connection with this finding, Dr L Boominathan, Director-cum-chief scientist of GBMD, reports that: Mechanistic insights into Cancer therapy: NOS-2 increases the levels of cell cycle protein Cyclin D1 via up regulation of its target gene. This study provides mechanistic insights into why increased expression of NOS-2 promotes tumorigenesis, while inhibition of its expression improves caner therapy.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
To cite: Boominathan, Mechanistic insights into Cancer therapy: NOS-2 increases the levels of cell cycle protein Cyclin D1 via up regulation of its target gene, 11/March/2014, 13.47, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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