April

April 28, 2014

Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of tumor suppressor RECK via up regulation of its target miRNA, 28/April/2014, 7.17 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of tumor […]
April 28, 2014

Unravelling the mechanism of Lifespan extension: The induced pluripotent stem cell gene Lin-28 extends the life span of an organism by down regulating its target gene, 28/April/2014, 6.58 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Unravelling the mechanism of Lifespan extension: The induced pluripotent stem cell gene Lin-28 extends the life […]
April 28, 2014

Therapeutic insights into restoring the contractility of heart muscle function: Treatment with the Smoothened inhibitor Saridegib (and its analogs) improves cardiac contractility and function via down regulation of its target gene, 28/April/2014, 6.49 am

A study from University of California, San Diego, and Sanford-Burnham Medical Research Institute, La Jolla, California, USA shows that Inhibition of miR-25 improves cardiac contractility in the failing heart. This study was […]
April 28, 2014

From Apoptotic sensitivity to Chemoresistance: Withaferin A, an arthritis drug, suppresses the expression of pro-apoptotic protein BIM via up regulation of its target, 28/April/2014, 6.41 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, From Apoptotic sensitivity to Chemoresistance: Withaferin A, an arthritis drug, suppresses the expression of pro-apoptotic protein BIM via […]