A study from Watson School of Biological Sciences shows that SRSF1 is a critical transcriptional target of c-MYC. This study was published in the Feb 20, 2012 Cell Rep by Prof. Dr Krainer AR & Das, Watson School of Biological Sciences, USA.
On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Molecular cancer therapy: Tumor suppressor p53 suppresses the expression of SRSF1 via up regulation of its target gene. This data suggest that p53, by suppressing the expression of SRSF1, it will inhibit the expression of a number of oncogenic mRNAs in cancer cells.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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To cite: Boominathan, Molecular cancer therapy: Tumor suppressor p53 suppresses the expression of SRSF1 via up regulatin of its target gene, 11/May/2014, 8.09 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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