Insight into the treatment of Metastatic Pancreatic/intestine/ovarian Cancer: Tumor suppressor PTEN suppresses the expression of PDGF Receptor β via up regulation of its target gene, 7/May/2014, 15.13

The reprogramming protein Oct-4 positively regulates human GH expression via down regulation of its target gene, 7/May/2014, 15.09
May 7, 2014
Tumor suppression: MiRNA-133 increases the expression of Ink4d via down regulation of its target gene, 7/May/2014, 15.23
May 7, 2014
Show all

A study from Watson School of Biological Sciences shows that Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling. This study was published in the April 10, 2014 Cell by Prof. Dr Scott Lowe, Watson School of Biological Sciences, CSHL, New YorkProf. Dr Carol Prives, Department of Biological Sciences, Columbia University, New York; and others.

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that:  Insight into the treatment of Metastatic Pancreatic/intestine/ovarian Cancer: Tumor suppressor PTEN suppresses the expression of  PDGF Receptor β via up regulation of its target gene. Given that tumor suppressor p53 is mutated in about 50% of different human cancers, this study suggests, for the first time, a therapeutic strategy as to how mutant p53 expressing human cancers can be cured.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

To citeBoominathanInsight into the treatment of Metastatic Pancreatic/intestine/ovarian Cancer: Tumor suppressor PTEN suppresses the expression of  PDGF Receptor β via up regulation of its target gene, 7/May/2014, 15.13, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

* Research cooperation

Comments are closed.