Insights into regulatory mechanisms that activate Oncogenic networks in human renal cancer: C/EBP-β increases the expression of oncogenic protein SPOP via down regulation of its target gene, 25/May/2014, 8.05 am

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A recent study from Institute for Genomics and Systems BiologyUniversity of Chicago and Argonne National Laboratory, Chicago, Illinois-IL 60637, USA; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA; and Section on Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL 60637, USA  shows that “SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub…” 

This study was published in the Apr 14 2014 Cancer Cell (One of the top journal in Cancer Biology with an IF of  of 24.755) by Prof. Dr Kevin P White, Li G and others from Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China; Laboratory of Disease Genomics and Individualized Medicine, Beijing Institute of Genomics; University of Chinese Academy of Sciences, Beijing 100049, China; Institute for Genomics and Systems Biology, University of Chicago and Argonne National Laboratory, Chicago, IL 60637, USA; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA etc.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Insights into regulatory mechanisms that activate Oncogenic networks in human renal cancerC/EBP-β increases the expression of oncogenic protein SPOP via down regulation of its target geneThis study unveils, for the time, as to how suppressing the expression of C/EBP-β in human cancers could be an effective therapeutic strategy in the treatment of various human cancers, including renal cancer.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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To citeBoominathan, Insights into regulatory mechanisms that activate Oncogenic networks in human renal cancerC/EBP-β increases the expression of oncogenic protein SPOP via down regulation of its target gene, 25/May/2014, 8.05 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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