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A study from Watson School of Biological Sciences shows that SRSF1 is a critical transcriptional target of c-MYC.  This study was published in the Feb 20, 2012 Cell  Rep by Prof. Dr Krainer AR & Das, Watson School of Biological Sciences, USA.

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Molecularly targeted therapy for cancer: RREB [Ras responsive element (RRE) binding protein] increases the expression of SRSF1 via up regulation of its target gene. This data suggest that RREB, by increasing the expression of SRSF1, it will increase the expression of a number of oncogenic mRNAs in cancer cells.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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To citeBoominathan, Molecularly targeted therapy for cancer: RREB [Ras responsive element (RRE) binding protein] increases the expression of SRSF1 via up regulation of its target gene,  13/May/2014, 6.01 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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