Monthly Archives: July 2014

Insights into improving the Radiosensitivity of Mammary cancer cells: Tetraindole inhibits UBQLN1-mediated autophagy and radio resisitance pathway via up regulation of its target gene, 05.21 am., 1/August/2014

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Insights into improving the Radiosensitivity of Mammary cancer cells: Tetraindole inhibits UBQLN1-mediated autophagy and radio resisitance pathway via up regulation of its target gene, 05.21 am., 1/August/2014,   Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you … Continue reading

Comments Off on Insights into improving the Radiosensitivity of Mammary cancer cells: Tetraindole inhibits UBQLN1-mediated autophagy and radio resisitance pathway via up regulation of its target gene, 05.21 am., 1/August/2014

MiRNA-based therapy for T2D: MiRNA-24 increases the expression of Lin-28 via down regulation of its target gene, 05.18 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, MiRNA-based therapy for T2D:  MiRNA-24 increases the expression of Lin-28 via down regulation of its target gene, 05.18 am., 1/August/2014,   Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * … Continue reading

Comments Off on MiRNA-based therapy for T2D: MiRNA-24 increases the expression of Lin-28 via down regulation of its target gene, 05.18 am

Insights into protecting the age-associated Endothelial dysfunction: Stress-induced tumor suppressor ARF aggravates hyperglycemia-induced endothelial dysfunction via up regulation of its target gene, 05.15 am., 1/August/2014

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Insights into protecting the age-associated Endothelial dysfunction: Stress-induced tumor suppressor ARF aggravates hyperglycemia-induced endothelial dysfunction via up regulation of its target gene, 05.16 am., 1/August/2014,   Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop … Continue reading

Comments Off on Insights into protecting the age-associated Endothelial dysfunction: Stress-induced tumor suppressor ARF aggravates hyperglycemia-induced endothelial dysfunction via up regulation of its target gene, 05.15 am., 1/August/2014

MiRNA-based therapy for Gastic carcinoma: TAp63 inhibits gastric cell metastasis via down regulation of ZEB2, 04.58 am., 1/August/2014

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, MiRNA-based therapy for Gastic carcinoma: TAp63 inhibits gastric cell metastasis via down regulation of ZEB2, 04.58 am., 1/August/2014,   Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation

Comments Off on MiRNA-based therapy for Gastic carcinoma: TAp63 inhibits gastric cell metastasis via down regulation of ZEB2, 04.58 am., 1/August/2014

MiRNA-based therapy for human cancers and Viral diseases: Tumor suppressor p53 increases the expression of IFN-γ via up regulation of its target miRNA, 04.55 am, 1/August/2014

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan,MiRNA-based therapy for human cancers and Viral diseases: Tumor suppressor p53 increases the expression of IFN-γ via up regulation of its target miRNA, 04.55 am., 1/August/2014,   Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite … Continue reading

Comments Off on MiRNA-based therapy for human cancers and Viral diseases: Tumor suppressor p53 increases the expression of IFN-γ via up regulation of its target miRNA, 04.55 am, 1/August/2014

Molecular mechanistic and therapeutic insights into Mycobacterium tuberculosis(M.tb)-induced tumorigenesis: M.tb suppresses the expression of p53 homologue p63 via up regulation of its target gene , 04.50 am., 1/August/2014

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Molecular mechanistic and therapeutic insights into Mycobacterium tuberculosis(M.tb)-induced tumorigenesis:  M.tb suppresses the expression of   p53 homologue p63 via up regulation of its target gene , 04.50 am., 1/August/2014,   Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you … Continue reading

Comments Off on Molecular mechanistic and therapeutic insights into Mycobacterium tuberculosis(M.tb)-induced tumorigenesis: M.tb suppresses the expression of p53 homologue p63 via up regulation of its target gene , 04.50 am., 1/August/2014

Anti-miRNA-based therapy for Hypertension: The tumor suppressor p53 disrupts APLN-APJ axis via up regulation of its target gene, 31/July/2014, 13.45

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan,  L., Anti-miRNA-based therapy for Hypertension: The tumor suppressor p53 disrupts APLN-APJ axis via up regulation of its target gene, 31/July/2014, 13.45, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org  * Research cooperation

Comments Off on Anti-miRNA-based therapy for Hypertension: The tumor suppressor p53 disrupts APLN-APJ axis via up regulation of its target gene, 31/July/2014, 13.45

MiRNAs-based therapy for Miocardial diseases: MiRNA-24 increases angiogenesis, decreases infarct size and improves heart function via down regulation of its target gene, 31/July/2014, 09.17 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan,  MiRNAs-based therapy for Miocardial diseases: MiRNA-24 increases angiogenesis, decreases infarct size and improves heart function via down regulation of its target gene, 31/July/2014, 09.17  am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop … Continue reading

Comments Off on MiRNAs-based therapy for Miocardial diseases: MiRNA-24 increases angiogenesis, decreases infarct size and improves heart function via down regulation of its target gene, 31/July/2014, 09.17 am

Insights into the regulation of memory, learning, metabolism, ageing and longevity: BDNF (Brain-derived neurotrophic factor) suppresses the expression of Sirtuin1 via up regulation of its target gene, 31/July/2014, 09.13 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan,  Insights into the regulation of memory, learning, metabolism, ageing and longevity: BDNF (Brain-derived neurotrophic factor) suppresses the expression of Sirtuin1 via up regulation of its target gene, 31/July/2014, 09.13  am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When … Continue reading

Comments Off on Insights into the regulation of memory, learning, metabolism, ageing and longevity: BDNF (Brain-derived neurotrophic factor) suppresses the expression of Sirtuin1 via up regulation of its target gene, 31/July/2014, 09.13 am

Natural product-based therapy for Metastatic tumors: Celastrol, a compound isolated from the herb “Thunder of God Vine", suppresses the expression of MMP-9 via down regulation of its target gene, 31/July/2014, 08.41 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Natural product-based therapy for Metastatic tumors: Celastrol, a compound isolated from the herb “Thunder of God Vine”, suppresses the expression of MMP-9 via down regulation of its target gene, 31/July/2014, 08.41 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org … Continue reading

Comments Off on Natural product-based therapy for Metastatic tumors: Celastrol, a compound isolated from the herb “Thunder of God Vine", suppresses the expression of MMP-9 via down regulation of its target gene, 31/July/2014, 08.41 am

Natural product-based therapy for Metastatic tumors: Celastrol, a compound isolated from the herb “Thunder of God Vine”, suppresses the expression of MMP-9 via down regulation of its target gene, 31/July/2014, 08.41 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Natural product-based therapy for Metastatic tumors: Celastrol, a compound isolated from the herb “Thunder of God Vine”, suppresses the expression of MMP-9 via down regulation of its target gene, 31/July/2014, 08.41 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org … Continue reading

Comments Off on Natural product-based therapy for Metastatic tumors: Celastrol, a compound isolated from the herb “Thunder of God Vine”, suppresses the expression of MMP-9 via down regulation of its target gene, 31/July/2014, 08.41 am

MiRNA-based therapy for T2D: MiRNA-24 inhibits the processing of let-7 miRNA via down regulation of its target gene, 31/July/2014, 08.11 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, MiRNA-based therapy for T2D:  MiRNA-24 inhibits the processing of let-7 miRNA via down regulation of its target gene, 31/July/2014, 08.11 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org  * … Continue reading

Comments Off on MiRNA-based therapy for T2D: MiRNA-24 inhibits the processing of let-7 miRNA via down regulation of its target gene, 31/July/2014, 08.11 am

Natural-based therapy for Drug resistant-Mammary carcinomas: Rhamnetin, an O-methylated flavonol isolated from cloves, overcomes Herceptin drug resistance in Patients with Mammary cancer, 31/July/2014, 07.40 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Natural-based therapy for Drug resistant-Mammary carcinomas: Rhamnetin, an O-methylated flavonol isolated from cloves, overcomes Herceptin drug resistance in Patients with Mammary cancer, 31/July/2014, 07.39 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org … Continue reading

Comments Off on Natural-based therapy for Drug resistant-Mammary carcinomas: Rhamnetin, an O-methylated flavonol isolated from cloves, overcomes Herceptin drug resistance in Patients with Mammary cancer, 31/July/2014, 07.40 am

Mechanistic insights into tumor suppression: PAPD5 increases the expression of tumor suppressor TPM1 via down regulation of its target gene, 31/July/2014, 06.34 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Mechanistic insights into tumor suppression: PAPD5 increases the expression of tumor suppressor TPM1 via down regulation of its target gene, 31/July/2014, 06.34 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a … Continue reading

Comments Off on Mechanistic insights into tumor suppression: PAPD5 increases the expression of tumor suppressor TPM1 via down regulation of its target gene, 31/July/2014, 06.34 am

MiRNA-based treatment for Growth hormone/Growth hormone receptor-related pathopathologies: Tumor suppressosor p53 suppresses the expression of Growth hormone receptor via up regulation of its target gene, 31/July/2014, 6.31 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan,  L., MiRNA-based treatment for Growth hormone/Growth hormone receptor-related pathopathologies: Tumor suppressosor p53 suppresses the expression of Growth hormone receptor via up regulation of its target gene, 31/July/2014, 6.31 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When … Continue reading

Comments Off on MiRNA-based treatment for Growth hormone/Growth hormone receptor-related pathopathologies: Tumor suppressosor p53 suppresses the expression of Growth hormone receptor via up regulation of its target gene, 31/July/2014, 6.31 am

Insights into protecting the age-associated Endothelial dysfunction: Snail/SNAI1 protects against hyperglycemia-induced endothelial dysfunction via up regulation of its target gene, 31/July/2014, 05.43 am

A recent study from the National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China shows that “Repression of P66Shc expression by Sirtuin-1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction.” This … Continue reading

Comments Off on Insights into protecting the age-associated Endothelial dysfunction: Snail/SNAI1 protects against hyperglycemia-induced endothelial dysfunction via up regulation of its target gene, 31/July/2014, 05.43 am

Vitamins-based therapy for Psoriasis: 1α,25-dihydroxyvitamin D(3) inhibits psoriasiform skin inflammation via up regulation of its target gene, 31/July/2014, 5.36 am

A recent study from the Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA; and Institute for Biomedical Research, University College London, London, UK shows that “Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation.” This study … Continue reading

Comments Off on Vitamins-based therapy for Psoriasis: 1α,25-dihydroxyvitamin D(3) inhibits psoriasiform skin inflammation via up regulation of its target gene, 31/July/2014, 5.36 am

MiRNA-based treatment for T1D/T2D: Yes-associated protein increases insulin producing cell mass and function via up regulation of its target gene, 31/July/2014, 5.28 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan,  L., MiRNA-based treatment for T1D/T2D: Yes-associated protein increases insulin producing cell mass and function via up regulation of its target gene, 31/July/2014, 5.28 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us … Continue reading

Comments Off on MiRNA-based treatment for T1D/T2D: Yes-associated protein increases insulin producing cell mass and function via up regulation of its target gene, 31/July/2014, 5.28 am

MiRNA-based therapy for Gastic carcinoma: Tumor suppressor p53 homologue TAp63 inhibits gastric cell metastasis via down regulation of OPN (Osteopontin), 31/July/2014, 5.18 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan,  L., MiRNA-based therapy for Gastic carcinoma: Tumor suppressor p53 homologue TAp63 inhibits gastric cell metastasis via down regulation of OPN (Osteopontin), 31/July/2014, 5.18 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us … Continue reading

Comments Off on MiRNA-based therapy for Gastic carcinoma: Tumor suppressor p53 homologue TAp63 inhibits gastric cell metastasis via down regulation of OPN (Osteopontin), 31/July/2014, 5.18 am

MiRNA-based stem cell therapy for Myocardial disorders: MiRNA-421 enhances Mesenchymal stem cell therapy for Myocardial infarction via suppression of its target gene, 31/July/2014, 5.14 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan,  L., MiRNA-based stem cell therapy for Myocardial disorders: MiRNA-421 enhances Mesenchymal stem  cell therapy for Myocardial infarction via suppression of its target gene, 31/July/2014, 5.14 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop … Continue reading

Comments Off on MiRNA-based stem cell therapy for Myocardial disorders: MiRNA-421 enhances Mesenchymal stem cell therapy for Myocardial infarction via suppression of its target gene, 31/July/2014, 5.14 am