Mechanistic & Therapeutic insights into Motile Ciliogenesis & Respiratory dysfunction (Primary cilia dyskinesia): Metformin, the widely used drug to treat NIDDM, increases Cilia length and number via up regulation of its target gene, 24/July/2014, 5.31 am

Molecular and Therapeutic insights into Osteoclastogenesis and its associated disorders: Metformin, the widely used drug to treat NIDDM, inhibits osteoporosis and bone metastasis, 23/July/2014, 8,13 am
July 23, 2014
Anti-miRNA based therapy for NIDDM: Increased expression of Stress-responsive MiRNA-26a promotes gluconeogenesis and hyperglycemia via down regulation of Cyclin D1, Genome-2-Bio-Medicine Discovery center (GBMD), 24/07/2014, 5.46 am
July 23, 2014
Show all

A study from Division of Cellular and Developmental Biology, MCB Department, University of California at Berkeley, Berkeley, California, USA has reported that “miR-34/449 miRNAs are required for motile ciliogenesis by..”

This study was published in the 04 June 2014 Nature (IF: 38.597) by Prof. Lin He, Song Rui and others from Division of Cellular and Developmental Biology, MCB Department, University of California at Berkeley, Berkeley, California, USA.  

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Mechanistic & Therapeutic insights into Motile Ciliogenesis & Respiratory dysfunction (Primary cilia dyskinesia): Metformin, the widely  used drug to treat NIDDM, increases Cilia length and number via up regulation of its target gene. This study suggests that Metformin may alleviate respiratory dysfunction that is commonly found in disease conditions such as Primary cilia dyskinesia.  Together, this study suggests that pharmacological formulations encompassing “Metformin or its closely-related analogues” can be used, either alone, or in combination with other drugs, to treat Primary cilia dyskinesia.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

To citeBoominathan, Mechanistic & Therapeutic insights into Motile Ciliogenesis & Respiratory dysfunction (Primary cilia dyskinesia): Metformin, the widely  used drug to treat NIDDM, increases Cilia length and number via up regulation of its target gene, 24/July/2014, 5..30 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

* Research cooperation

Comments are closed.