Mechanistic & Therapeutic insights into Motile Ciliogenesis & Respiratory dysfunction (Primary cilia dyskinesia): Genistein increases Cilia length and number via up regulation of its target gene, 28/July/2014, 5.33 am

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A study from Division of Cellular and Developmental Biology, MCB Department, University of California at Berkeley, Berkeley, California, USA has reported that “miR-34/449 miRNAs are required for motile ciliogenesis by..”

This study was published in the 04 June 2014 Nature (IF: 38.597by Prof. Lin He, Song Rui and others from Division of Cellular and Developmental Biology, MCB Department, University of California at Berkeley, Berkeley, California, USA.  

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Mechanistic & Therapeutic insights into Motile Ciliogenesis & Respiratory dysfunction (Primary cilia dyskinesia): Genistein increases Cilia length and number via up regulation of its target gene. This study suggests that  derivatives of Genistein may alleviate respiratory dysfunction that is commonly found in disease conditions such as Primary cilia dyskinesia.  Together, this study suggests that pharmacological formulations encompassing “derivatives of Genistein can be used, either alone, or in combination with other drugs, to treat Primary cilia dyskinesia.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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To citeBoominathan, Mechanistic & Therapeutic insights into Motile Ciliogenesis & Respiratory dysfunction (Primary cilia dyskinesia): Genistein increases Cilia length and number via up regulation of its target gene, 28/July/2014, 5.33 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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