Vitamin-based therapy for Tuberculosis: δ-tocotrienol (a derivative of Vitamin-E) inhibits the pathogenesis and progression of tuberculosis (Mtb) via up regulation of its target gene, 13/July/2014, 7.26 am

Natural product-based treatment for Metastatic Pancreatic/intestine/ovarian Cancer: Luteolin, an antioxidant flavanoid, suppresses the expression of PDGF Receptor β via up regulation of its target gene, 13/July/2014, 7.13 am
July 13, 2014
Mechanistic insights into Metastasis: Tumor suppressor ING1b inhibits invasion and metastasis via down regulation of ubiquitin specific peptidase 25, 14/July/2014, 4.50 am
July 13, 2014
Show all

A study from the Immunobiology Section, Laboratory of Parasitic DiseasesNational Institute of Allergy and Infectious DiseasesNational Institutes of Health, Bethesda, USA has reported that “Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk.”

This study was published in the June 25, 2014 Nature by Prof. Sher, Mayer-Barber Katrin D and others from the Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA.

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Vitamin-based therapy for Tuberculosis:  δ-tocotrienol (a derivative of Vitamin-E) inhibits the pathogenesis and progression of tuberculosis (Mtb) via up regulation of its target gene.  This study suggests that δ-tocotrienol (a derivative of Vitamin-E), by down regulating its target gene, it may increase the levels of lipid inflammatory mediator Prostaglandin E2. Thereby, it will inhibit the pathogenesis and progression of tuberculosis. Together, this study suggests that pharmacological formulations encompassing “δ-tocotrienol (a derivative of Vitamin-E) or its analogues” can be used to inhibit the progression of tuberculosis. 

Idea Proposed/Formulated by: Dr L Boominathan PhD

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

Courtesy: When you cite drop us a line at info@genomediscovery.org

CitationBoominathan, Vitamin-based therapy for Tuberculosis:  δ-tocotrienol (a derivative of Vitamin-E) inhibits the pathogenesis and progression of tuberculosis (Mtb) via up regulation of its target gene, 13/July/2014, 7.26 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Web: http://genomediscovery.org

*Research cooperation

Comments are closed.