Insights into the treatment of Hepatocellular carcinomas and Cholangiocarcinomas: MiRNA-124 regulates the emergence of p53 mutant tumors via down regulation of its target gene, 5/August/2014, 11.03 am

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A recent study from Koch Institute of Integrative Cancer Research, Department of Biology, MIT, Cambridge, USA  shows that p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular…. Liver Cancer.” This study was published in the July 31  2014 Cell (The number 1 journal in Basic biology) by Prof  Scott W. Lowe, Darjus F. Tschaharganeh, and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Insights into the treatment of Hepatocellular carcinomas and Cholangiocarcinomas: MiRNA-124 regulates the emergence of p53 mutant tumors via down regulation of its target geneThis study suggests that MiRNA-124, by decreasing the expression of Nestin, it may inhibit the emergence of p53 mutant hepatocellular carcinomas, Cholangiocarcinomas and other tumors.  Together, this study suggests that pharmacological formulations encompassingMiRNA-124 activators” may be used to treat Hepatocellular carcinomas and Cholangiocarcinomas.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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To citeBoominathan, Insights into the treatment of Hepatocellular carcinomas and Cholangiocarcinomas: MiRNA-107 regulates the emergence of p53 mutant tumors via down regulation of its target gene, 5/August/2014, 11.03 am,  Genome-2-Bio-Medicine Discovery center (GBMD)http://genomediscovery.org

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