Mechanistic and therapeutic insights into the treatment of Psoriasis: GATA Binding Protein-6 inhibits psoriasiform skin inflammation via up regulation of its target gene, 3/August/2014, 5.53 am

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A recent study from the Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA; and Institute for Biomedical Research, University College London, London, UK shows that “Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation.” This study was published in the Apr 23  2014 Nature by Prof Ulrich H. von AndrianLorena Riol-Blanco, and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Mechanistic and therapeutic insights into the treatment of Psoriasis: GATA Binding Protein-6 inhibits psoriasiform skin inflammation via up regulation of its target geneThis study suggests that GATA Binding Protein-6, by increasing the expression of its target gene, it may alleviate the interleukin-23-mediated psoriasiform skin inflammationTogether, this study suggests that pharmacological formulations encompassing“GATA Binding Protein-6 activators” may be used to treat psoriasiform skin inflammation.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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To citeBoominathan, L., Mechanistic and therapeutic insights into the treatment of Psoriasis: GATA Binding Protein-6 inhibits psoriasiform skin inflammation via up regulation of its target gene, 3/August/2014, 5.53 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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