MiRNA-based therapy for Cancer: MIRNA-190b increases the expression of tumor suppressor p53 via down regulation of its target gene, 22/September/2014, 22.59

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, MiRNA-based therapy for Cancer: MIRNA-190b increases the expression of tumor suppressor p53 via down regulation of its target gene, 22/September/2014, 22.59, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: p53 is the most mutated gene in human cancer.  MIRNA-190b, by suppressing the expression of its target gene, it could induce the expression of p53. […]

Therapeutic insights into he treatment of stroke, multiple sclerosis, and Alzheimer’s disease: Stem cell protien Oct-4 promotes neuroprotection via up regulation of its target gene, 22/September/2014, 15.01

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Therapeutic insights into he treatment of stroke, multiple sclerosis, and Alzheimer’s disease: Stem cell protien Oct-4 promotes neuroprotection via up regulation of its target gene, 22/September/2014, 15.-01, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org Significance: This study suggests that Oct-4, by down regulating the expression of […]

Interleukin-mediated metastatic tumor suppression: Pro-inflammatory cytokine IL-1β suppresses the expression of oncogene NEDD9 and inhibits metasatic progression via up regulation of its target gene, 22/September/2014, 14.51

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan,  Interleukin-mediated metastatic tumor suppression:  Pro-inflammatory cytokine IL-1β suppresses the expression of oncogene  NEDD9 and inhibits metasatic progression via up regulation of its target gene, 22/September/2014, 14.51, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org Significance: This study suggests that IL-1β, by increasing the expression of its target […]

Small RNA-based therapy for Myocardial Infarction: MiRNA-566 improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 22/September/2014, 12.33 pm

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the March 7  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Small RNA-based therapy for Myocardial Infarction: MIRNA-566 improves myocardial function after myocardial infarction via  up […]

Small RNA-based “Insulin sensitizing therapy” for DM: AntagomiR-195 functions as an “insulin sensitizer” via up regulation of its target gene, Genome-2-Bio-Medicine Discovery center (GBMD), 22/September/2014, 09.53 am

A recent study from the Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California, USA; Center for Liver, Departments of Pediatrics and Laboratory Medicine, University of Groningen, University Medical Center Groningen, The Netherlands; Department of Biochemistry-Molecular Pharmacology, New York University School of Medicine, New York, New York, USA; Department of Medicine, Division of Endocrinology and […]

MiRNAs-based therapy for Alopecia areata: A pharmacological mixture encompassing miRNA-375 and miRNA-17 reverses Alopecia areata via down regulation of its target genes, Genome-2-Bio-Medicine Discovery center (GBMD), 22/September/2014, 09.09 am

A recent study from the Department of Pathology, Columbia University, New York, New York, USA;  Department of Dermatology, Columbia University, New York, New York, USA; and Department of Medicine, Columbia University, New York, New York, USA shows that “Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition.” This study was published in the August, 17 […]