Anti-miRNA based therapy for Osteoporosis: Stress-induced miRNA-145 increases the expression of a bone formation inhibitor Sclerostin via up regulation of its target gene, 08/September/2014, 06.38 am

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, L., Anti-miRNA based therapy for Osteoporosis: Stress-induced miRNA-145 increases the expression of a bone formation inhibitor Sclerostin via up regulation of its target gene, 08/September/2014, 06.38 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests, for the first time, that miRNA-145 may inhibit bone formation.  Thus, pharmacological formulations encompassing “MiRNA-145 inhibitor” may be used to treat Osteoporosis.

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