AntiMiRNA-based therapy for Myocardial Infarction: Stress-induced protein Sirtuin-6 inhibits myocardial function after myocardial infarction via down regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10, 09/September/2014, 06.04 am

MiRNA-based therapy for Osteoporosis: MiRNA-125b suppresses the expression of a bone formation inhibitor Sclerostin via down regulation of its target gene, 09/September/2014, 05.53 am
September 9, 2014
Anti-miRNA based therapy for T2D: Over-expression of Stress-responsive MiRNA-449a promotes gluconeogenesis and hyperglycemia via down regulation of Cyclin D1, Genome-2-Bio-Medicine Discovery center (GBMD), 09/September/2014, 6.10 am
September 9, 2014
Show all

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the March 7  2013 issue of Nature  by Prof Dimmler, Boon, and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: AntiMiRNA-based therapy for Myocardial Infarction: Stress-induced protein Sirtuin-6 inhibits myocardial function after myocardial infarction via down regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10. By increasing the expression of Sirtuin-6 in cardiomyocytes, one may prevent ageing-associated decline in cardiac function.  Together, this study suggests that pharmacological formulations encompassing Sirtuin-6 or its activators” may be used to improve cardiac function after myocardial infarction.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

To citeBoominathan,  L., AntiMiRNA-based therapy for Myocardial Infarction: Stress-induced protein Sirtuin-6 inhibits myocardial function after myocardial infarction via down regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10, 09/September/2014,  06.04 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

* Research cooperation

Comments are closed.