Interleukin-based therapy for DM: Inflammatory cytokine Interleukin-27 (IL-27) inhibits gluconeogenesis and hyperglycemia via up regulation of Cyclin D1, Genome-2-Bio-Medicine Discovery center (GBMD), 12/September/2014, 05.49 am

Molecular mechanisms of tumor suppression: Interleukin-1β (IL-1β) suppresses the expression of immortality gene telomerase via up regulation of its target gene, 12/September/2014, 5.35 am
September 12, 2014
Vitamin-based therapy for DM: 1,25-dihydroxyvitamin D3 increases insulin-secreting cell mass and function via down regulation of its target gene, 12/September/2014, 06.59 am
September 12, 2014
Show all

A study from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, USA shows that Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression.”

This study was published in the June 26, 2014 Natur[I.F >35] by Prof. Puigserver and others from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, USA.

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMDreports here that: Interleukin-based therapy for DM: Inflammatory cytokine Interleukin-27 (IL-27) inhibits gluconeogenesis and hyperglycemia via up regulation of Cyclin D1.  This study suggests that IL-27, by down regulating its target gene, it may inhibit gluconeogenesis and hyperglycemia. Together, this study suggests that pharmacological formulations encompassing IL-27 or its activators   may be used in the treatment of DM.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

To citeBoominathan, L., Interleukin-based therapy for DM: Inflammatory cytokine Interleukin-27 (IL-27) inhibits gluconeogenesis and hyperglycemia via up regulation of Cyclin D1., Genome-2-Bio-Medicine Discovery center (GBMD), 12/September/2014, 05.49 am.,  http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

* Research cooperation

Comments are closed.