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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Insights into mechanisms that inhibit the development of DM: CDX2 increases the expression of a positive regulator of insulin transcription, NeuroD1 via down regulation of its target gene, 7/September/2014, 05.58 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance:  This study suggests, for the first time, that CDX2, by decreasing its downstream target gene, it may increase the expression of an activator of insulin transcription, NeuroD1.  This data suggests that “CDX2 activators” may be used to treat DM.

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