Mechanistic and therapeutic insights into rejuvenating ageing immune cells in DM patients: High glucose levels decrease telomerase activity and promote senescence of human T cells via up regulation of their target gene, 5/September/2014, 08.03 am

MiRNAs-based therapy for Alopecia areata: A pharmacological mixture containing miRNA-375 and miRNA-17 reverses Alopecia areata via down regulation of its target genes, Genome-2-Bio-Medicine Discovery center (GBMD), 05/09/2014, 7.57 am
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Teacher’s day special

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We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2014) will be available to the use of Scientists/Professors/Physicians/Researchers for free.

So, there will be no terms and conditions for the ideas posted today (05/September/2014). Each idea posted will be served first come, first served basis.Write to info@genomediscovery.org for more details about the idea posted.

Dr L Boominathan PhD

CEO & CSO, GBMD.

A recent study from the Division of Infection and Immunity, University College London, London, UK shows that “The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells.” This study was published in the August 24  2014 Nature Immunology  by Prof Arne N AkbarAlessio Lanna and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Mechanistic and therapeutic insights into rejuvenating ageing immune cells in DM patients: High glucose levels decrease telomerase activity and promote senescence of human T cells via up regulation of their target gene. High glucose, by decreasing telomerase activity in immune cells, it may accelerate ageing-associated decline in immune function Together, this finding may aid in devising a strategy to prevent accelerated ageing of immune cells in DM  patients.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

To citeBoominathan, L., Mechanistic and therapeutic insights into rejuvenating ageing immune cells in DM patients: High glucose levels decrease telomerase activity and promote senescence of human T cells via up regulation of their target gene, 5/September/2014,  08.03 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

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