Menatetrenone, a vitamin K2 analogue, promotes gluconeogenesis and hyperglycemia via down regulation of Cyclin D1, 13/September/2014, 8.10 am

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A study from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, USA shows that Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression.”

This study was published in the June 26, 2014 Nature [I.F >35] by Prof. Puigserver and others from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, USA.

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Menatetrenone, a vitamin K2 analogue, promotes gluconeogenesis and hyperglycemia via down regulation of Cyclin D1.  This study suggests that Menatetrenone, by down regulating its target gene, it may promote  gluconeogenesis and hyperglycemia.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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To citeBoominathan, L., Menatetrenone, a vitamin K2 analogue, promotes gluconeogenesis and hyperglycemia via down regulation of Cyclin D1, 13/September/2014, 8.10 am.,  http://genomediscovery.org

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