MiRNAs-based therapy for Alopecia areata: A pharmacological mixture containing miRNA-375 and miRNA-17 reverses Alopecia areata via down regulation of its target genes, Genome-2-Bio-Medicine Discovery center (GBMD), 05/09/2014, 7.57 am

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Teacher’s day special

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We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2014) will be available to the use of Scientists/Professors/Physicians/Researchers for free.

So, there will be no terms and conditions for the ideas posted today (05/September/2014). Each idea posted will be served first come, first served basis.Write to info@genomediscovery.org for more details about the idea posted.

Dr L Boominathan PhD

CEO & CSO, GBMD.

A recent study from the Department of Pathology, Columbia University, New York, New York, USA;  Department of Dermatology, Columbia University, New York, New York, USA; and Department of Medicine, Columbia University, New York, New York, USA shows that “Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition.”

This study was published in the August, 17 2014 issue of Nature Medicine (The number 1 journal in Medicine with an IF of ~35) by Prof. Clynes R, Xing L and others from the Department of Pathology, Columbia University, New York, New York, USA;  Department of Dermatology, Columbia University, New York, New York, USA; and Department of Medicine, Columbia University, New York, New York, USA

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: MiRNAs-based therapy for Alopecia areata: A pharmacological mixture containing miRNA-375 and miRNA-17 reverses Alopecia areata via down regulation of its target genes.  This study suggests, for the first time, that miRNA-375 and miRNA-17, by up regulating their target genes, they may reverse alopecia areata  Together, this study suggests that pharmacological formulations encompassing ” miRNA-375 and miRNA-17 or small molecule compounds that activate the expression of  miRNA-375 and miRNA-17 may be used to treat Alopecia areata.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

To citeBoominathan, L., MiRNAs-based therapy for Alopecia areata: A pharmacological mixture  containing miRNA-375 and miRNA-17 reverses Alopecia areata via down regulation of its target genes, Genome-2-Bio-Medicine Discovery center (GBMD), 05/09/2014, 7.57 am,  http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

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