Molecular therapy for Human Cancer: Resistin suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target genes, 15/September/2014, 6.39 am

Natural product-based therapy for Pulmonary arterial hypertension: Curcumin, the major component of turmeric, protects against development of pulmonary arterial hypertension via up regulation of its target gene , 15/September/2014, 06.28 am
September 15, 2014
Therapeutic insights into the treatment of hippocampal neurodegeneration and memory loss: Stress induced miR-185 promotes memory loss through induction of apoptosis of hippocampal neurons, 15/September/2014, 06.47 am
September 15, 2014
Show all

The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; I.F: >35) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This study provides mechanistic insights into how TPP1 regulates telomerase function.

In connection with this finding, Dr Boominathan, Founder Director-cum-chief scientist of GBMDreports that: Molecular therapy for Human Cancer: Resistin suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target genes Remarkably, over 90% human tumors over express telomerase, suggesting that inhibition of its activity may increase the efficacy of anticancer therapy.  Together, this study suggests that pharmacological formulations encompassing “Resistin or its activators” can be used to treat human cancers.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

To citeBoominathan,   Molecular therapy for Human Cancer: Resistin suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target genes, 15/September/2014, 6.39 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

* Research cooperation

Comments are closed.