Therapetic insights into tissue homeostasis and inflammation: Triptolide, a natural compound found in the herb Thunder of God vine, maintains intestinal epithelial cell homeostasis via up regulation of RIPK1, 09/September/2014, 07.04 am

Anti-miRNA based therapy for T2D: Over-expression of Stress-responsive MiRNA-449a promotes gluconeogenesis and hyperglycemia via down regulation of Cyclin D1, Genome-2-Bio-Medicine Discovery center (GBMD), 09/September/2014, 6.10 am
September 9, 2014
MiRNA-based Regenerative therapy for DM: MiRNA-375 promotes reprogramming of adult pancreatic ductal cells into α, δ, and β cells via up regulation of Ngn3, 09/September/2014, 9.03 am
September 9, 2014
Show all

A recent study from the Institute for Genetics, Centre for Molecular Medicine (CMMC), and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany shows that “RIPK1 maintains epithelial homeostasis by inhibiting apoptosis …

 This study was published in the August 17  2014 issue of Nature (The number 1 journal in Science with an I.F of  42) by Prof Manolis PasparakisMarius Dannappel and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Therapeutic insights into  tissue homeostasis and inflammation: Triptolide, a natural compound found in the herb Thunder of God vine,  maintains intestinal epithelial cell homeostasis via up regulation of  RIPK1. Triptolide, by decreasing the expression of its target gene in intestinal cells, it may increase the expression of RIPK1.  Thereby, it may prevent intestinal inflammation and inhibit apoptosis.  Together, this study suggests that pharmacological formulations encompassing Triptolide or its analogues” may be used to inhibit intestinal inflammation.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

To citeBoominathan, Therapetic insights into  tissue homeostasis and inflammation: Triptolidea natural compound found in the herb Thunder of God vine,  maintains intestinal epithelial cell homeostasis via up regulation of  RIPK1, 09/September/2014,  07.04 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

* Research cooperation

Comments are closed.