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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Therapeutic insights into Protecing Genome integrity:  Stem cell protein Oct-4 increases the expression of an oncogenic protein Aurora B via up regulation of its target gene, 26/September/2014, 08.38 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests that Oct-4, by increasing the expression of its target gene, it  may promote oncogenesis.  Thus, pharmacological formulations encompassing “Oct-4 inhibitor” may be used to enhance genome integrity and prevent tumorigenesis. 

* Research cooperation

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