Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Therapeutic insights into Protecing Genome integrity: Stem cell protein Oct-4 increases the expression of an oncogenic protein Aurora B via up regulation of its target gene, 26/September/2014, 08.38 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that Oct-4, by increasing the expression of its target gene, it may promote oncogenesis. Thus, pharmacological formulations encompassing “Oct-4 inhibitor” may be used to enhance genome integrity and prevent tumorigenesis.
* Research cooperation