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October 1, 2014

Anti-cancer stem cell therapeutics: Campothecin (CPT) inhibits mammary cancer stem cell proliferation via down regulation of Wnt receptor FZD7, 01/October/2014, 14.50

A study from the Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA shows that “ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast […]
October 1, 2014

Natural product-based anti-metastasis therapy: Luteolin, a flavone with an antioxidant and anti-inflammatory activity, suppresses the expression of transcription coactivator peroxisome proliferator-activated receptor gamma, coactivator 1 alpha and inhibits metastasis via up regulation of its target gene, 01/October/2014, 11.19 am

A study from the Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA shows that Peroxisome proliferator-activated receptor gamma, coactivator 1 […]
October 1, 2014

MiRNA-based therapy for Human Cancer: MiRNA-28 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 01/October/2014, 10.01 am

The 1989 Nobel prize winner in Chemistry Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; I.F: >42) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This […]
October 1, 2014

Chemopreventive therapy: Germinated brown rice (GBR) inhibits tumor cell proliferation via down regulation of Superoxide dismutase 1 (SOD1), 01/October/2014, 09.10 am

The 1989 Nobel prize winner in Physiology/Medicine Prof. Varmus Harold E, Somwar R and others from High Throughput Screening Core Facility, and Organic Synthesis Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; and US National […]