05

October 5, 2014

Treating cancer with a longevity-promoting drug: Acarbose, the widely used drug in the treatment of NIDDM, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via down regulation of its target genes, 6/October/2014, 5.27 am

The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the University of Colorado BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; I.F: >42) stating that “The TEL patch of telomere protein TPP1 mediates telomerase […]
October 5, 2014

Natural product-based therapy for Human cancer: (6)-gingerol (6G), the pungent component of Ginger, inhibits tumor cell proliferation via down regulation of Superoxide dismutase 1 (SOD1), 6/October/2014, 5.06 am

The 1989 Nobel prize winner in Physiology/Medicine Prof. Varmus Harold E, Somwar R and others from High Throughput Screening Core Facility, and Organic Synthesis Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; and the US National […]
October 5, 2014

Interleukin-based Differentiation therapy for Human Leukaemia: Interleukin-1β (IL-1β) functions as an anti-cancer barrier by promoting differentiation of leukaemic cells via up regulation of Histone methyl-transferase MLL4, 6/October/2014, 4.50 am

A recent study from the Laboratory of Genome Integrity, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA shows that “DNA-damage-induced differentiation of leukaemic cells as an […]
October 5, 2014

Regenerative Stem cell therapy for Myocardial Infarction: Lin-28 improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 6/October/2014, 04.39 am

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. […]