MiRNA-based therapy for Psoriasis: MiRNA-145 aggravates psoriasiform skin inflammation via down regulation of its target gene, 02/October/2014, 08.31 am

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On the eve of Mahatma Gandhi Birth Anniversary

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We wish everyone a happy Mahatma Gandhi Jayanti 2014. On this special occasion, we are happy to announce that Ideas posted today (02/October/2014) will be available to the use of Scientists/Professors/Physicians/Researchers for free. So, there will be no terms and conditions for the ideas posted today (02/October/2014). Each idea posted will be served first come, first served basis. For more details, you may write to us at info@genomediscovery.org.

Dr L Boominathan PhD

CEO  & CSO, GBMD.

A recent study from the Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA; and Institute for Biomedical Research, University College London, London, UK shows that “Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation.” This study was published in the Apr 23  2014 Nature by Prof Ulrich H. von AndrianLorena Riol-Blancoand others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: MiRNA-based therapy for Psoriasis: MiRNA-145 aggravates psoriasiform skin inflammation via down regulation of its target geneThis study suggests that MiRNA-145, by decreasing the expression of its target gene, it may increase the interleukin-23-mediated psoriasiform skin inflammationTogether, this study suggests that pharmacological formulations encompassing “Anti-MiRNA-145 or MiRNA-145 suppressors” may be used to treat psoriasiform skin inflammation.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

To citeBoominathan, L., MiRNA-based therapy for Psoriasis: MiRNA-145 aggravates psoriasiform skin inflammation via down regulation of its target gene, 02/October/2014, 08.31 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

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