Chemopreventive therapy against Human Cancer: Citrus aurantium flavonoids inhibit tumor cell proliferation via down regulation of Superoxide dismutase 1 (SOD1), 28/October/2014, 08.07 am
The 1989 Nobel prize winner in Physiology/Medicine Prof. Varmus Harold E, Somwar R and others from High Throughput Screening Core Facility, and Organic Synthesis Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; and the US National Cancer Institute, USA has published a research paper in the 27 September 2011 issue of Proc Natl Acad Sci U S A. (I.F: >10) stating that “Superoxide dismutase 1 (SOD1) is a target for a small molecule […]
Natural product-based therapy for traumatic brain injury (TBI): Chaihuang-Yishen granule (CHYS), a traditional Chinese medicine, alleviates apoptosis of neuronal cells after traumatic brain injury via up regulation of its target gene, 28/October/2014, 8.01 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, Natural product-based therapy for traumatic brain injury (TBI): Chaihuang-Yishen granule (CHYS), a traditional Chinese medicine, alleviates apoptosis of neuronal cells after traumatic brain injury via up regulation of its target gene, 28/October/2014, 8.01 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests that Chaihuang-Yishen granule (CHYS), by increasing the expression of […]
MiRNA-based therapy for Cancer: MiRNA-146 inhibits proliferation and promotes senescence through up regulation of tumor suppressor LKB1, 28/October/2014, 07.41 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, MiRNA-based therapy for Cancer: MiRNA-146 inhibits proliferation and promotes senescence through up regulation of tumor suppressor LKB1, 28/October/2014, 07.41 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests that tumor suppressor MiRNA-146, by decreasing the expression of its target gene, it may increase the expression of tumor suppressor LKB1. Thus, pharmacological formulations encompassing “MiRNA-146 or its activators“ may be used […]
Molecular therapy for Hypertension: BCL6 rescues pulmonary arterial hypertension via down regulation of its target gene, 28/October/2014, 07.37 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, Molecular therapy for Hypertension: BCL6 rescues pulmonary arterial hypertension via down regulation of its target gene, 28/October/2014, 07.36 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests that BCL6, by decreasing the expression of its target gene, it may rescue pulmonary arterial hypertension. Thus, pharmacological formulations encompassing “BCL6 activators“ may be used to treat pulmonary arterial hypertension. Amount: $300 Undisclosed information: A […]
Insights into the treatment of Fibrosis: Stem cell protein Oct4 suppresses the expression of TGFß receptor II (TGFBR2) and extracellular matrix proteins via up regulation of its target gene, 28/October/2014, 07.32
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, Insights into the treatment of Fibrosis: Stem cell protein Oct4 suppresses the expression of TGFß receptor II (TGFBR2) and extracellular matrix proteins via up regulation of its target gene, 28/October/2014, 07.32, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests that Stem cell protein Oct4, by increasing the expression of its target gene, it may decrease the expression of TGFß […]
Anti-metastasis therapy: Angiopoietin-like protein 1 suppresses the expression of NEDD9 via up regulation of its target gene, 28/October/2014, 7.30 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, L., Anti-metastasis therapy: Angiopoietin-like protein 1 suppresses the expression of NEDD9 via up regulation of its target gene, 28/October/2014, 7.30 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests that Angiopoietin-like protein 1, by increasing the expression of its target gene, it may decrease the expression of NEDD9. Thus, pharmacological formulations encompassing “Angiopoietin-like protein 1 activators“ may be used to inhibit tumorigenesis […]
