Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, L., Anti-metastasis therapy: Angiopoietin-like protein 1 suppresses the expression of SMAD3 via up regulation of its target gene, 31/October/2014, 5.43 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Significance: This study suggests that Angiopoietin-like protein 1, by increasing the expression of its target gene, it may decrease the expression of SMAD3. Thus, pharmacological formulations encompassing “Angiopoietin-like protein 1 activators“ may be used to inhibit tumorigenesis and metastasis.
Undisclosed information: A mechanistic insight into how Angiopoietin-like protein 1 decreases the expression of SMAD3.
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