Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, Mechanistic & therapeutic insights into tumorigenesis: SNAI2 increases the expression of MiR-17-92 via down regulation of its target gene, 20/October/2014, 6.39 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that IL-1β, by decreasing the expression of its target gene, it may increase the expression of oncogenic MiR-17-92. Thus, pharmacological formulations encompassing “SNAI2 suppressors“ may be used to inhibit tumorigenesis and metastasis.