Molecular therapy for DM: TET3 promotes gluconeogenesis and hyperglycemia via up regulation of Cyclin D1, 29/September/2014, 06.33 am

Natural product-based therapy for traumatic brain injury (TBI): Neurotensin (NT) alleviates apoptosis of neuronal cells after traumatic brain injury via up regulation of its target gene, 29/October/2014, 5.46 am
October 29, 2014
Therapetic insights into the treatment of T2DM and Cardiovascular disorders: Cell cycle-regulated protein E2F1 increases the expression of stem cell and reprogramming protein Lin28 via up regulation of its target gene, 28/October/2014, 07.23 am
October 29, 2014
Show all

A study from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA; and others shows that “Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression.”

This study was published in the June 26, 2014 Nature [I.F >42] by Prof. Puigserver and others from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Molecular therapy for DM:  TET3 promotes gluconeogenesis and hyperglycemia via down regulation of Cyclin D1. This study may suggest that TET3,  by up regulating its target gene, it may inhibit  gluconeogenesis and hyperglycemia. Together, this study suggests that pharmacological formulations encompassing “TET3 or its activators”  may be used to treat NIDDM.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

Terms & Conditions applhttp://genomediscovery.org/registration/terms-and-conditions/

To citeBoominathan, L., Molecular therapy for DM: TET3 promotes gluconeogenesis and hyperglycemia via up regulation of Cyclin D1, 29/September/2014, 06.33 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

* Research cooperation

Comments are closed.