October

October 9, 2014

Small Molecule-based anti-metastasis therapy: Rubone suppresses the expression of transcription coactivator peroxisome proliferator-activated receptor gamma, coactivator 1 alpha and inhibits metastasis via up regulation of its target gene, 9/October/2014, 14.13

A study from the Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA shows that Peroxisome proliferator-activated receptor gamma, coactivator 1 […]
October 9, 2014

MiRNA-based therapy for Chronic Myelogenous Leukemia (CML): MiRNA-29 eradicates CML leukemia stem cells via activation of p53, 9/October/2014, 9.06 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, MiRNA-based therapy for Chronic Myelogenous Leukemia (CML): MiRNA-29 eradicates CML leukemia stem cells via activation of p53, 9/October/2014, 9.06 am, Genome-2-Bio-Medicine Discovery […]
October 9, 2014

Natural product-based therapy for Human Cancer: Garlic suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 9/October/2014, 8.59 am

The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; I.F: >35) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This […]
October 9, 2014

Natural product-based therapy for Myocardial Infarction: Icariin, a flavanoid and a PDE-5 inhibitor, improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 9/October/2014, 6.43 am

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March   2013 issue of Nature [I.F: >42] by Prof Dimmler, […]