Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
To cite: Boominathan, Therapetic insights into the treatment of T2DM and Cardiovascular disorders: Cell cycle-regulated protein E2F1 increases the expression of stem cell and reprogramming protein Lin28 via up regulation of its target gene, 28/October/2014, 07.23 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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* Research cooperation
Undisclosed information: An insight into how E2F1 decreases insulin resistance and alleviates cardiovascular dysfunction.
Significance: This study suggests, for the first time, that E2F1, by increasing the expression of its target gene, it may increase insulin sensitivity; and promote the survival of cardiomyocytes. Together, this study suggests that pharmacological formulations encompassing “E2F1 activators” may be used to treat metabolic disorders, including T2DM and cardiac diseases.