Therapetic insights into the treatment of T2DM and Cardiovascular disorders: Cell cycle-regulated protein E2F1 increases the expression of stem cell and reprogramming protein Lin28 via up regulation of its target gene, 28/October/2014, 07.23 am

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

Webhttp://genomediscovery.org

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To citeBoominathan, Therapetic insights into the treatment of T2DM and Cardiovascular disorders: Cell cycle-regulated protein E2F1 increases the expression of stem cell and reprogramming protein Lin28 via up regulation of its target gene, 28/October/2014, 07.23 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Undisclosed information: An insight into how E2F1 decreases insulin resistance and alleviates cardiovascular dysfunction.  

Significance: This study suggests, for the first time, that  E2F1, by increasing the expression of its target gene, it may increase insulin sensitivity; and promote the survival of cardiomyocytesTogether, this study suggests that pharmacological formulations encompassing “E2F1 activators” may be used to treat metabolic disorders, including T2DM and cardiac diseases.

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