Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, Transcriptional Regulation: Menin (MEN1) decreases the expression of transcriptional coactivator p300 via up regulation of its target gene, 03/October/2014, 11.18 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that Menin (MEN1) , by decreasing the expression of its target gene, it may decrease the expression of p300. Thus, pharmacological formulations encompassing “MEN1 activators“ may be used to inhibit tumorigenesis and metastasis.