Transcriptional Regulation: Menin (MEN1) decreases the expression of transcriptional coactivator p300 via up regulation of its target gene, 03/October/2014, 11.17 am

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

CitationBoominathan, Transcriptional Regulation: Menin (MEN1) decreases the expression of transcriptional coactivator p300 via up regulation of its target gene, 03/October/2014, 11.18 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests that Menin (MEN1) , by decreasing the expression of its target gene, it may decrease the expression of p300.  Thus, pharmacological formulations encompassing MEN1 activators may be used to inhibit tumorigenesis and metastasis.

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