Natural product-based therapy for Cancer: Combination of Quercetin and Hyperoside (QH) increases the expression of the tumor suppressor TPM1 via down regulation of its target gene, 1/November/2014, 22.31

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Natural product-based therapy for Cancer: Combination of Quercetin and Hyperoside (QH) increases the expression of the tumor suppressor TPM1 via down regulation of its target gene, 1/November/2014, 22.31,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Amount: $ 300*** Undisclosed information: A mechanistic insight […]

Expose yourself to optimal level of sunlinght to evade cancer: 1,25-dihydroxyvitamin D increases miRNA biogenesis and promotes tumor regression via down regulation of its target gene, 1/November/2014, 9.51 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan,  Expose yourself to optimal level of sunlinght to evade cancer: 1,25-dihydroxyvitamin D increases miRNA biogenesis and promotes tumor regression via down regulation of its target gene, 1/November/2014, 9.51 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Significance: This study provides […]

Anti-metastasis therapy: Angiopoietin-like protein 1 suppresses the expression of stem cell protein Oct4 via up regulation of its target gene, 1/November/2014, 8.37 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, L., Anti-metastasis therapy: Angiopoietin-like protein 1 suppresses the expression of stem cell protein Oct4 via up regulation of its target gene, 1/November/2014, 8.37 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests that Angiopoietin-like protein 1, by increasing the expression of its target gene, it may decrease the expression of Oct-4.  Thus, pharmacological formulations encompassing “Angiopoietin-like protein 1 activators“ may be […]

MiRNA-based therapy for Cancer: p53 up regulates the expression of tumor suppressor LKB1 through induction of its target miRNA, 1/November/2014, 8.33 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, MiRNA-based therapy for Cancer: p53 up regulates the expression of tumor suppressor LKB1 through induction of its target miRNA, 1/November/2014, 8.33 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests that p53, by increasing the expression of its target miRNA, it may increase the expression of tumor suppressor LKB1. Thus, pharmacological formulations encompassing “p53 activators“ may be used to treat LKB1-mutated human […]

Chemopreventive therapy against metastatic cancer: Germinated brown rice (GBR) inhibits cancer cell metastasis via down regulation of ubiquitin specific peptidase 25, 1/November/2014, 8.10 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Chemopreventive therapy against metastatic cancer: Germinated brown rice (GBR) inhibits cancer cell metastasis via down regulation of  ubiquitin specific peptidase 25, 1/November/2014, 8.10 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Amount: $ 300 Undisclosed information: A mechanistic insight into how Germinated brown rice (GBR)  decreases […]

Therapeutic insights into the treatment of hypertension, endothelial dysfunction and cardiovascular diseases: Neurotensin promotes endothelium-dependent vasorelaxation via up regulation of its target gene, 1/November/2014, 08.00 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, Therapeutic insights into the treatment of hypertension, endothelial dysfunction and cardiovascular diseases: Neurotensin promotes endothelium-dependent vasorelaxation via up regulation of its target gene, 1/November/2014, 08.00 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests that Neurotensin, by decreasing the expression of its target gene,  it may rescue pulmonary arterial hypertension. Thus, pharmacological formulations encompassing “Neurotensin activators“ may be used to […]