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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Natural product-based antimetastatic therapy: Rhamnetin, an O-methylated flavonol isolated from cloves, suppresses the expression L1CAM via up regulation of its target gene, 31/January/20145, 23.07, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests, for the first time, that Rhamnetin, by increasing the expression of its target gene, it may inhibit the expression of L1CAM. Thereby, it may inhibit the migration and invasion of prostate cancer cells. Thus, pharmacological formulations encompassing “Rhamnetin or its analogues”  can be used to inhibit the progression of metastatic human tumors

Amount: $ 300

Undisclosed information: How Rhamnetin suppresses the expression of L1CAM.

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