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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Preserving the function of the guardian of the genome, p53:  Rhamnetin, an O-methylated flavonol isolated from cloves, inhibits functional inactivation of p53 by somatic mutation and viral oncognes via up regulation of its target gene, 28/January/20145, 8.20 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests, for the first time, that Rhamnetin, by increasing the expression of its target gene, it may inhibit the functional inactivation of p53 by somatic mutation and viral oncognes. Thereby, it may safeguard the function of the guardian of the genome, p53. Thus, pharmacological formulations encompassing “Rhamnetin or its analogues”  may be used to inhibit the development of human tumors

Amount: $ 500

Undisclosed information: How Rhamnetin preserves the function of the guardian of the genome, p53

Web: http://genomediscovery.org

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