MiRNA-based Regenerative therapy for DM: p-ΔNp63α increases insulin-secreting cell mass and function via down regulation of its target genes, 15/February/2015, 20.04

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, MiRNA-based Regenerative therapy for DM: p-ΔNp63α increases insulin-secreting cell mass and function via down regulation of its target genes, 15/February/2015, 20.04 , Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests, for the first time, that p-ΔNp63α, by decreasing the expression of its target gene, it may increase insulin-secreting cell mass and function. Thereby, it may increase […]

Mechanistic insight into DNA repair: BMP-6 increases the expression of DNA repair protein hMSH2 via down regulation of its target gene, 15/February/2015, 19.59

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Mechanistic insight into DNA repair: BMP-6 increases  the expression of DNA repair protein hMSH2 via down regulation of its target gene, 15/February/2015, 20.00, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests, for the first time, that BMP-6, by decreasing the expression of its target gene, it may increase the expression of DNA repair […]

Regenerative Stem cell therapy for Myocardial Infarction: HOXA11 improves ageing- and stress-associated decline in cardiac function via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 15/February/2015, 19.57

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Regenerative Stem cell therapy for Myocardial Infarction: HOXA11 improves ageing- and stress-associated decline in cardiac function via  up regulation of PNUTS/PPP1R10 […]

Vitamin-based therapy for cancer: Sunshine Vitamin suppresses the expression of AML1 and MMP-13 via up regulation of its target gene, 15/February/20145, 19.47

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Vitamin-based therapy for cancer: Sunshine Vitamin suppresses the expression of AML1 and MMP-13 via up regulation of its target gene, 15/February/20145, 19.47, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests, for the first time, that Sunshine Vitamin, by decreasing the expression of  its target genes, it may inhibit the expression of […]