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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Natural product-based therapy for Hepatocellular carcinoma: Celastrol increases  the expression of hepatocellular carcinoma, downregulated 1 (HEPN1) and inhibits the progression of hepatocellular carcinoma via down regulation of its target gene, 21/February/2015, 22.48, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests, for the first time, that Celastrolby decreasing the expression of its target gene, it may increase the expression of HEPN1. Thereby, it may inhibit the progression of Hepatocellular carcinoma. Thus, pharmacological formulations encompassing “Celastrol or its analogues”  can be used to treat Hepatocellular carcinoma.

Amount: $ 300

Undisclosed information: How Celastrol increases the expression of HEPN1

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