AntagomiR-based therapy for Ischemic heart disease: Expression of AntagomiR-146b in bone-derived marrow cells mediates cardiac repair after myocardial infarction via down regulation of its target gene, 18/February/2015, 9.53 am

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, AntagomiR-based therapy for Ischemic heart disease: Expression of AntagomiR-146b in bone-derived marrow cells mediates cardiac repair after myocardial infarction via down regulation of its target gene, 18/February/2015, 9.53 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests, for the first time, that AntagomiR-146b, by suppressing the expression of its target gene, it may promote cardiac repair after myocardial infarction.  Thus, pharmacological formulations encompassing “AntagomiR-146b  or inhibitors of miR-146b  may be used to promote cardiac repair.

Amount: $ 300*

Undisclosed information: How miR-146b inhibits cardiac repair after myocardial infarction

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