Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, MiRNA-based anti-metastasis therapy: Tumor suppressor MiRNAs-15a and -16 suppress the expression L1CAM via down regulation of their target genes, 15/February/20145, 19.52, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that tumor suppressor MiRNAs-15a and -16, by decreasing the expression of their target genes, they may inhibit the expression of L1CAM. Thereby, they may inhibit the migration and invasion of cancer cells. Thus, pharmacological formulations encompassing “MiRNA-15/16 activators” can be used to inhibit metastatic human tumors.
Amount: $ 300*
Undisclosed information: How MiRNAs-15a and -16 suppress the expression of L1CAM.
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* Research cooperation