MiRNA-based anti-metastasis therapy: Tumor suppressor MiRNAs-15a and -16 suppress the expression L1CAM via down regulation of their target gene, 15/February/20145, 19.52

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, MiRNA-based anti-metastasis therapy: Tumor suppressor MiRNAs-15a and -16 suppress the expression L1CAM via down regulation of their target genes, 15/February/20145, 19.52, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests, for the first time, that tumor suppressor MiRNAs-15a and -16, by decreasing the expression of  their target genes, they may inhibit the expression of L1CAM. Thereby, they may inhibit the migration and invasion of cancer cells. Thus, pharmacological formulations encompassing “MiRNA-15/16 activators”  can be used to inhibit metastatic human tumors

Amount: $ 300*

Undisclosed information: How MiRNAs-15a and -16 suppress the expression of L1CAM.

Web: http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

* Research cooperation

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