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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, MiRNA-based anticancer therapy: Tumor suppressor MiRNA-203 suppresses the expression L1CAM via down regulation of its target genes, 19/February/2015, 21.45, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests, for the first time, that tumor suppressor MiRNA-203, by decreasing the expression of  its target gene, it may inhibit the expression of L1CAM. Thereby, it may inhibit  migration and invasion of cancer cells. Thus, pharmacological formulations encompassing “MiRNA-203 activators”  can be used to inhibit metastatic human tumors

Amount: $ 300

Undisclosed information: How MiRNA-203 suppresses the expression of L1CAM.

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