Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, MiRNA-based Regenerative therapy for DM: p63-miR-130 pathway increases insulin-secreting cell mass and function via down regulation of its target genes, 14/February/2015, 11.23 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that p53, by increasing the expression of its target gene miRNA-130, it may increase insulin-secreting cell mass and function. Thereby, it may increase the insulin sensitivity of cellular tissues. Thus, pharmacological formulations encompassing “p63/MiRNA-130 activators” can be used to treat DM.
Amount: $ 500*
Undisclosed information: How p63-miRNA-130 pathway increases insulin-secreting cell mass and function.
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* Research cooperation