MiRNA-based Regenerative therapy for DM: p63-miR-130 pathway increases insulin-secreting cell mass and function via down regulation of its target genes, 14/February/2015, 11.23 am

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

CitationBoominathan, MiRNA-based Regenerative therapy for DM: p63-miR-130 pathway increases insulin-secreting cell mass and function via down regulation of its target genes, 14/February/2015, 11.23 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests, for the first time, that p53, by increasing the expression of its target gene miRNA-130, it may increase insulin-secreting cell mass and functionThereby, it may increase the insulin sensitivity of cellular tissues.  Thus, pharmacological formulations encompassing “p63/MiRNA-130 activators”  can be used to treat DM.

Amount: $ 500*

Undisclosed information: How p63-miRNA-130 pathway increases insulin-secreting cell mass and function. 

Web: http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

* Research cooperation

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