Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, MiRNA-based therapy for Human cancers: Let-7b increases the expression of tumor suppressor p53/p73 via down regulation of its target gene, 18/February/2015, 23.11, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that MiRNA Let-7b, by decreasing the expression of its target gene, it may increase the expression of p53/p73. Thereby, it may inhibit the progression of human cancers, including p53-mutated human cancers. Thus, pharmacological formulations encompassing “Let-7b or its activators” can be used to treat human cancers.
Amount: $ 500*
Undisclosed information: How Let-7b increases the expression of p53/p73
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* Research cooperation