Natural product-based therapy for Human Cancer: Genistein suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 28/February/2015, 16.29

Natural product-based therapy for Melonama: Rhamnetin , an O-methylated flavonol isolated from cloves, increases the expression of ADAR1 and inhibits melanoma progression via down regulation of its target gene, 28/February/2015, 8.51 am
February 28, 2015
Natural product-based antiviral therapy: Genistein attenuates influenza A virus (IAV) infection via down regulation of its target gene, 28/February/2015, 17.00
February 28, 2015
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National Science day special

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We wish every one a very happy National Science day. On this special occasion, we are happy to announce that ideas posted today (28/February/2015) will be available to the use of Scientists/Professors/Teachers/Physicians/Researchers for free. So, there will be no terms and conditions for the ideas posted today (28/February/2015). Each idea posted will be served first come, first served basis.Write to info@genomediscovery.org for more details. 

 

Dr L Boominathan PhD

President & CSO, GBMD.

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The 1989 Noble prize winner in Chemistry, Prof. Thomas R. Cech, from the University of Colorado BioFrontiers Institute, USA, has published a research paper in the 13 December 2012 Nature (492(7428):285-9; I.F: >35) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This study provides mechanistic insights into how TPP1 regulates telomerase function.

In connection with this finding, Dr Boominathan, Founder Director-cum-chief scientist of GBMD, reports that: Natural product-based therapy for Human Cancer: Genistein suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene Remarkably, over 90% human tumors over express telomerase, suggesting that inhibition of its activity may increase the efficacy of anticancer therapy.  Together, this study suggests that pharmacological formulations containing “Genistein or its analogues” can be used in the treatment of human cancers.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

To citeBoominathan,   Natural product-based therapy for Human Cancer: Genistein suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 28/February/2015, 16.31,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

* Research cooperation

Undisclosed information: How Genistein suppresses the expression of TPP1

Amount: $500*

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