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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Natural product-based therapy for Metastatic tumors: Sulindac, an anti-inflammatory drug, increases the expression of tumor suppressor TPM1 via down regulation of its target gene, 26/February/2015, 11.40 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests, for the first time, that Sulindac, by suppressing the expression of its target geneit may increase the expression of TPM1. Thereby, it may inhibit tumor progressionThus, pharmacological formulations encompassing “Sulindac or its analogues”  may be used to inhibit the progression of tumors.

Amount: $ 300

Undisclosed information: How Sulindac increases the expression of TPM1

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