Mechanistic insight into Regulation of Ribosome biogenesis: NR2F2 suppresses the expression of RNA polymerase I via down regulation of its target gene, 22/February/2015, 16.24
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Mechanistic insight into Regulation of Ribosome biogenesis: NR2F2 suppresses the expression of RNA polymerase I via down regulation of its target gene, 22/February/2015, 16.24, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests, for the first time, that tumor suppressor NR2F2, by increasing the expression of its target gene, it may decrease […]
Mechanistic insights into tumor suppression: Ribosomal protein L11 suppresses the expression of immortality gene telomerase via down regulation of its target gene, 22/February/2015, 16.20
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Mechanistic insights into tumor suppression: Ribosomal protein L11 suppresses the expression of immortality gene telomerase via down regulation of its target gene, 22/February/2015, 16.20, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests, for the first time, that Ribosomal protein L11, by suppressing the expression of its target gene, it may decrease […]
Mechanistic insights into tumor suppression: Ribosomal protein S14 suppresses the expression of oncomiR 17-92 via down regulation of its target gene, 22/February/2015, 16.14
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Mechanistic insights into tumor suppression: Ribosomal protein S14 suppresses the expression of oncomiR 17-92 via down regulation of its target gene, 22/February/2015, 16.14, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests, for the first time, that Ribosomal protein S14, by suppressing the expression of its target gene, it may decrease the […]
Natural product-based Life-extension therapy: Epigallocatechin-3-Gallate, the major component of Green tea, increases life span by inducing the expression of its target gene, 22/February/2015, 11.27 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Significance: Epigallocatechin-3-Gallate, the major component of Green tea, may increase life span by inducing its target gene. Together, pharmacological formulations encompassing “Epigallocatechin-3-Gallate or its analogues“ may function as longevity-promoting agents. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan: Natural product-based Life-extension therapy: Epigallocatechin-3-Gallate, the major component of Green tea, increases life span by inducing the expression of its target gene, 22/February/2015, 11.27 […]
Molecular based therapy for NIDDM: Jagged1 inhibits gluconeogenesis and hyperglycemia via up regulation of CyclinD1, 22/February/2014, 9.13 am
A study from the Department of Cancer Biology, Dana-Farber Cancer Institute; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA; and others shows that “Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression.” This study was published in the June 26, 2014 Nature [I.F >42] by Prof. Puigserver and others from the Department of Cancer Biology, Dana-Farber Cancer Institute; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, […]
MiRNA-based molecular therapy for Right ventricular cardiomyopathy: Repressor-element-1-silencing transcription factor suppresses arrhythmogenic right ventricular cardiomyopathy via down regulation of its target gene, 22/February/2015, 12.09 am
A recent study from the Ludwig Institute for Cancer Research Limited, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom shows that “iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy ….” This study was published in the 17 February 2015 issue of Proc Natl Acad Sci U S A by Prof Xin Lu, Dr. […]
